Table 1.
Details of Infection Phenotype-Associated Polymorphisms within Pcl7.
| Nucleotide Position | Base: Infectious | Base: Noninfectious | Amino Acid: Infectious | Amino Acid: Noninfectious |
|---|---|---|---|---|
| 678 | T (one G exception: P37+) | C/G | G (synonymous) | G (synonymous) |
| 689 | A (one G exception: P37+) | G/T | Y (one W exception: P37+) | G/F/W |
| 690 | T (one G exception: P37+) | G/C | ||
| 691 | T | G (one T exception: P1032−) | S (one A exception: P37+) | A/V (one S exception: P1032−) |
| 693 | G | A | ||
| 691 | G | T/C | A/E | Y/H |
| 695 | C (one A exception: P37+) | A | ||
| 696 | A | T | ||
| 702 | T (one A exception: P37+) | A | G (synonymous) | G (synonymous) |
| 703 | G | A | G/V | S |
| 705 | A (one C exception: P37+) | T/C | ||
| 707 | G (one C exception: P37+) | A/C | G/A | E/S |
| 708 | T (one A exception: P37+) | A | ||
| 710 | C | G/T | A/T | G/V |
| 713 | G (one T exception: P37+) | C/T | G/F | A/V |
| 714 | A (one C exception: P37+) | C | ||
| 716 | C (one A exception: P37+) | A | A (one Y exception: P37+) | Y/E |
| 728 | C | T | A | V |
| 829 | G (one T exception: P1006+) | T | A (one S exception: P1006+) | L/S |
| 832 | T | C/G | S | P/G/A |
| 841 | G (one C exception: P37+) | C | G (one L exception: P37+) | L/R |
Note: Nucleotide and corresponding amino acid positions are based on translation-based alignment (supplementary fig. 2, supplementary material online). Gray shading indicates positions where infection phenotype is not perfectly correlated with nucleotide sequence, protein sequence, or both.