Table 1. Deletion of neuronal A1AR has no effect on baseline body temperature or physical activity.
Sex | Adora1fl Female | Adora1fl;Syn1-Cre Female | P | Adora1fl Male | Adora1fl;Syn1-Cre Male | P |
---|---|---|---|---|---|---|
N | 4 | 5 | 7 | 8 | ||
Tb, light phase (°C) | 36.17 ±0.07 | 36.40 ±0.16 | 0.27 | 35.67 ±0.16 | 35.76 ±0.12 | 0.64 |
Tb, dark phase (°C) | 37.37 ±0.17 | 37.39 ±0.16 | 0.94 | 36.77 ±0.13 | 36.93 ±0.05 | 0.25 |
ΔTb, dark-light (°C) | 1.21 ±0.10 | 0.99 ±0.25 | 0.50 | 1.10 ±0.10 | 1.17 ±0.11 | 0.64 |
Tb span (°C) | 2.58 ±0.15 | 2.09 ±0.45 | 0.38 | 2.28 ±0.08 | 2.49 ±0.14 | 0.23 |
Activity, light phase (counts) | 6.8 ±0.5 | 8.1 ±0.6 | 0.18 | 5.4 ±0.3 | 6.4 ±0.4 | 0.09 |
Activity, dark phase (counts) | 19.6 ±1.1 | 25.0 ±3.5 | 0.23 | 14.5 ±1.0 | 15.5 ±1.1 | 0.51 |
Data collected from 5-month old mice over a continuous 96-hour interval. Tb span is the 95th minus the 5th percentiles. Data are mean ± SEM. P values are from unpaired t-tests comparing genotype within sex.