Table 3. Relationship between LDL-C levels estimated with the Friedewald and Martin methods and the methylation levels of the LPL, ADRB3, MTHFR genes and habitual dietary intake.
| Model 3—Response variable: LDL-C Friedewald | ||||
|---|---|---|---|---|
| Variable | Coefficient | LB-UB (95%) | Z statistic | p-value |
| Intercept | 109.10 | 98.16 ± 120.04 | 9.97 | >0.000 |
| LPL gene (%) | 10.85 | -2.83 ± 24.53 | 0.79 | 0.428 |
| ADRB3 gene (%) | -8.93 | -23.73 ± 5.87 | -0.60 | 0.547 |
| MTHFR gene (%) | 10.02 | -5.42 ± 25.46 | 0.65 | 0.517 |
| Cholesterol (mg) | 0.03 | 0.02 ± 0.05 | 2.15 | 0.033* |
Model adjusted for the intake of the nutrients were included in the explanatory model; *: p < 0.005; LDL- C: low-density lipoprotein cholesterol; LB: lower boundary; UB: Upper boundary. No significant relationship was found in this model for Martin.