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Diagnosis of HCC using single or combinations of markers.
| Sensitivity (%) | Specificity (%) | Accuracy (%) | |
|---|---|---|---|
| Single marker | |||
| GP73 | 76.34 | 80.09 | 79.61 |
| AFP | 55.6 | 86.7 | 73.4 |
| GGT | 68.4 | 97.1 | 84.8 |
| DKK-1 | 93.6 | 86.9 | 89.08 |
| Combination with GP73 | |||
| GP73 + AFP | 89.2 | 85.2 | 96 |
| GP73 + AFP-L3 | 78.49 | 85.03 | 84.19 |
| GP73 + GGT | 91.1 | 77.1 | 83.2 |
| GP73 + DKK-1 | 97.4 | 93.1 | 94.5 |
Abbreviations: AFP, alpha-fetoprotein; DKK-1, dickkopf-1; GGT, gamma-glutamyl transferase; GP73, Golgi protein 73; HCC, hepatocellular carcinoma.
