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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Liver Res. 2020 Sep 25;4(4):161–167. doi: 10.1016/j.livres.2020.09.003

Table 2.

Factors that regulate GP73 expression.

Regulators Factors GP73 expression
Virus HBsAg, HCV Up
Cytokines IL-6, IFN-γ, IL-1, IL-8 Up
TNF-α Down
Proteins HIF-2α, mTORC1, Up
NF-κB (p50) Down
miRNAs miR-141–3p, miR-382, miR-27b, miR-212, miR-132, miR-493–5p Down

Abbreviations: GP73, Golgi protein 73; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus; HIF-2α, hypoxia inducible factors-2alpha; IFN-γ, interferon-gamma; IL, interleukin; miRNAs, microRNAs; mTORC1, mechanistic target of rapamycin complex 1; NF-κB, nuclear factor-kappa B; TNF-α, tumor necrosis factor-alpha.