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. 2020 Dec 16;554:83–88. doi: 10.1016/j.virol.2020.12.001

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© 2020 Elsevier Inc.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — Structure and cytotoxicity of GCs on ACE2^h cells. A. Structure of 7 GCs; B. ACE2 mRNA was overexpressed in ACE2_h cells compared to HEK293T cells. The experiments were repeat three times. Data are presented as mean ± S.D.; C. ACE2 was overexpressed in ACE2_h cells compared to HEK293T cells. The experiments were repeat three times. Data are presented as mean ± S.D. (***p < 0.001, compared with HEK293T); (***p < 0.001, compared with HEK293T); D. Cytotoxicity of GCs on ACE2^h cells under concentration from 0 to 400 μM. The experiments were repeat three times. Data are presented as mean ± S.D. (*p < 0.05, **p < 0.01, ***p < 0.001 compared to vehicle).