With the left PG as the seed region, the international standard ISSA induces specific changes in the brain region for FC (horizontal position). Note: the numbers represent different brain regions for FC. (1) Left cerebellum posterior lobe (uvula), (2) left cerebellum posterior lobe (declive), (3) left fusiform gyrus, (4) left lingual gyrus, (5) declive of the posterior left cerebellar lobe and the superior vermis, (6) left BA18, (7) left inferior occipital gyrus, (8) left cuneus (9) left BA19, (10) left precuneus, (11) left BA7, (12) right BA23 and median cingulate, (13) right median cingulate and inside-paracingulate (BA31), (14) right precuneus and BA19, (15) left BA40, (16) left precuneus and inside-paracingulate, (17) left inferior parietal gyrus, (18) left paracentral lobule, BA5, and inside-paracingulate, (19) left BA6, (20) left superior parietal gyrus.