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AdOSM-induced IL-33 expression is independent of IL-6. C57Bl/6 wild-type or IL6-/- mice were endotracheally administered AdOSM and whole lung cell lysates analyzed the expression of beta actin and (a) IL-33, phospho-STAT3/total STAT3 (pSTAT3/tSTAT3), or (b) IL-1 receptor accessory protein (IL-1RAcP), after 7 days by Western blotting. (c, d) Densitometry analysis of IL-33 and or IL-1RAcP (relative to actin) and of pSTAT3/tSTAT3 (c) (d). AU = arbitrary units. N =5/group. ∗p < .01.
