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. 2020 Dec 17;169:137–151. doi: 10.1016/j.addr.2020.12.008

Fig. 4.

Fig. 4

Inovio Pharmaceutical’s INO-4800 DNA vaccine elicits immune response in BALB/c mice. (A) Neutralization ID50 in naïve and INO-4800 immunized mice and (B) relative luminescence units (RLU) for sera from naïve and vaccinated mice. (C) Bronchoalveolar lavage fluid assayed for SARS-CoV-2 Spike protein-specific IgG antibodies by ELISA. (D) BAL dilution curves with raw OD 450 values. (E) T cell responses measured by IFN-γ ELISpot in splenocytes with overlapping peptide pools spanning the SARS-CoV-2 Spike protein. Reproduced with permission from [61].