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. 2020 Dec 3;14:587986. doi: 10.3389/fnins.2020.587986

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Copyright © 2020 Jeon, Lourenco, Kaiser, Waters, Scheulin, Fang, Kinder, Platt, Rothrock, Callaway, West and Park.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Stroke resulted in family level perturbations in gut microbiota between pre- and poststroke in MCAO pig model. Bacterial families showed changes in abundance (P ≤ 0.05) during the acute stage of stroke. P-value: Paired t-test comparing the mean prestroke values vs. each time point poststroke. Prestroke (PRE, n = 7), 1 day poststroke (1 DPS, n = 7), 3DPS (n = 6), and 5 DPS (n = 4).