Fig. 6.

FGF23 correlations (A) only two genes are correlated with Fgf23 transcription at both 10 and 23-week – Enpp1 and Spp1. (B) Correlation of Fgf23 with Enpp1 and Spp1 at 10 and 23 weeks in Enpp1^asj/asj and Enpp1^wt mice. Enpp1 transcription correlations with Fgf23 in both Enpp1^asj/asj and Enpp1^wt mice, but Spp1 correlates with Fgf23 in only Enpp1^asj/asj mice, suggesting that Spp1 transcription may be responding to ENPP1 deficiency rather than regulating Fgf23.