. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: J Struct Biol. 2020 Oct 21;212(3):107650. doi: 10.1016/j.jsb.2020.107650

Table 2:

Pearson correlation coefficients showing age-association for mechanical properties, morphology, mineral content and cross-link measures and stratified into pooled (n=33), wide (n=15), and narrow (n=15) groups. Significant correlations are shaded and marked by an asterisk;

	Mechanics			Morphology											Content
	Whole Bone Strength	Tissue-Level Strength	Tissue-Level Post-Yield Strain	(Total Area/Length)	Height	Bone Length	Perimeter	Total Area	Marrow Area	Cortical Area	Log(Porosity)	Pore Density	I.Max	I.Min	Ct.TMD	Water Content	Ash Content	Organic Content
Pooled	−0.27	−0.57^***	−0.61^***	0.38^*	0.03	0.06	0.41^*	0.33	0.2	0.28	0.47^**	0.02	0.20	0.36^*	−0.32	−0.33	0.23	0.21
Narrow	−0.15	−0.35	−0.41	0.68^**	0.03	0.39	0.74^**	0.73^**	0.56^*	0.21	0.49	0.15	0.49	0.69^**	−0.15	−0.35	0.24	0.32
Wide	−0.45	−0.73^**	−0.87^****	0.24	−0.13	−0.41	0.07	−0.05	−0.39	0.26	0.53^*	−0.36	−0.13	0.22	−0.52^*	−0.35	0.12	0.37

	Cross-Link Measures
	Log(Pyrrole)	Log(DPD)	Log(PYD)	DHLNL	HLNL	Log(PEN)	Total Immature	Log(Total Pyridinolines)	Total Mature	Total Enzymatic	Log(DHLNL/HLNL)	PYD/DPD	Log(Pyridinoline/Pyrrole)	Log(Immature/Mature)	Immature/Pyridinoline	Log(PEN/Total Enzymatic)	Log(PEN/Total Mature)	Log(PEN/Total Pyridinolines)
Pooled	−0.27	0.15	0.06	−0.34	0	0.77^****	−0.21	0.09	−0.08	−0.15	−0.3	−0.2	0.29	−0.2	−0.36^*	0.84^****	0.84^****	0.81^****
Narrow	0.02	0.4	0.25	−0.47	0.17	0.87^****	−0.2	0.3	0.25	0.02	−0.60^*	−0.33	0.31	−0.36	−0.54^*	0.85^****	0.87^****	0.86^****
Wide	−0.4	−0.26	−0.29	−0.15	−0.17	0.63^*	−0.19	−0.28	−0.36	−0.31	0.09	−0.13	0.07	0.2	0.15	0.81^***	0.82^***	0.80^***

p-value:

< 0.05,

^**

< 0.01,

^***

< 0.001,

^****

< 0.0001.