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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Eur J Med Chem. 2020 Sep 24;209:112866. doi: 10.1016/j.ejmech.2020.112866

Figure 1.

Figure 1.

Search for a new hit molecule using scaffold hopping approach. IC50 indicates compound concentration required to inhibit viability of the MDA-MB-231 triple-negative breast cancer cells by 50%. Data are expressed as the mean of three independent experiments, each performed in sextet.