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The expression of FGFR1 was significantly reduced by compound 4q. Representative images (left panel) and quantification (right panel) of pFGFR1 expression in MDA-MB-231 cells after 48 hours of treatment with compound 4q at the concentrations depicted in the presence and absence of natural ligand bFGF (n = 3). NS: no significance; *P < 0.05; **P<0.01.
