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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Eur J Med Chem. 2020 Sep 24;209:112866. doi: 10.1016/j.ejmech.2020.112866

Figure 3.

Figure 3.

Distribution of 4a in plasma and brain. Concentration (nM) of compound 4a in plasma and brain at 0, 0.5, 1, 6, 24, and 48 hours after single i.p. administration (10 mg/kg) was measured by liquid chromatography-tandem mass spectrometry. Data are expressed as the mean ± SEM of 2–4 independent experiments.