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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Pain. 2021 Jan;162(1):84–96. doi: 10.1097/j.pain.0000000000002005

Figure 6.

Figure 6.

IL-6 is increased and co-localized to subsets of cultured DRG neurons after paclitaxel incubation. The representative immunohistochemical images in (A) and (B) show that the expression of IL-6 (red) in the DRG is low in vehicle-treated culture incubated for 48 h but that there is a marked increase in expression in culture treated with paclitaxel and incubated for 48 h. Double immunohistochemical images shown in (C-H) indicate that IL-6 co-localized to MAP2 (green)-positive cells (C and D, co-localization indicated by yellow) and GFAP (blue)-positive cells (E and F, co-localization indicated by purple). Images G and H show IL-6, MAP-2, and GFAP labels merged. Scale bar=100 μm.