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. Author manuscript; available in PMC: 2021 Jun 15.
Published in final edited form as: Cancer Res. 2020 Nov 9;80(24):5543–5553. doi: 10.1158/0008-5472.CAN-20-2379

Figure 1. Gcn5 loss does not significantly alter normal B cell development in mice.

Figure 1.

A. Total cellularity of spleen of WT and CD19-Cre; Gcn5Fx/Fx mice 5-6-week-old mice (n=4 WT and n= 4 CD19-Cre; Gcn5Fx/Fx). B. Total femur cellularity of WT and CD19-Cre; Gcn5Fx/Fx 5-6-week-old mice (n=4 WT and n= 4 CD19-Cre; Gcn5Fx/Fx). C. Representative pictures and spleen weights of 5-6-week-old mice (n= 4 WT and n= 4 CD19-Cre Gcn5Fx/Fx). D. Quantification of flow cytometric analysis of B220+ bone marrow ProB (PI−B220+CD43hiIgM−) and PreB (PI−B220+CD43loIgM−) cells. E. Quantification of flow cytometric analysis of Immature (PI−B220+CD43loIgM+IgD−) and Mature (PI−B220+CD43loIgM−IgD+) B cells from bone marrow. Error bars represent mean ± SEM. For flow cytometric analysis n= 7 WT and n=5 CD19-Cre; Gcn5Fx/Fx mice. All p-values determined by unpaired Student’s t-test. *p≤ 0.05; **p≤ 0.01; ***p≤ 0.001; ****p≤ 0.0001.