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. 2020 Dec 3;11:587663. doi: 10.3389/fphar.2020.587663

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Copyright © 2020 Wang, Long, Huang, Zhang, Xie, Chen, Liu, Xiong and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BSHX decoction reduces diabetic metabolic parameters, urinary albumin excretion and ameliorates kidney function in DN mice. (A) Changes in body weight. (B) Changes in fasting blood glucose. (C) 24 h food intake. (D) 24 h water intake. (E) 24 h urine volume. (F) Serum triglyceride (TG). (G) Serum total cholesterol (TC). (H) Kidney weight/body weight. (I) Urinary albumin excretion rate (UAER). (J) Serum creatinine (SCr). (K) Blood urea nitrogen (BUN). ( L) Serum uric acid (SUA). n = 5–9 mice per group. All data are expressed as means ± SEM. ^* p < 0.05, ^* ^* p < 0.01, ^* ^* ^* p < 0.001 vs. the NC group; ^# p < 0.05, ^## p < 0.05, ^### p < 0.001 vs. DN model group.