Table 3.
Characteristics of the eight SLE patients with previously identified autoimmune liver disease (AILD).
| Sex/year of birth | F‐1939 | F‐1946 | F‐1956 | M‐1981 | F‐1939 | F‐1945 | F‐1977 | F‐1988 |
|---|---|---|---|---|---|---|---|---|
| Year of SLE diagnosis | 2008 | 1999 | 1983 | 2002 | 2001 | 2008 | 2017 | 1994 |
| Year of sampling | 2008 | 2010 | 2008 | 2009 | 2009 | 2009 | 2017 | 2010 |
| Year of AILD diagnosis | PBC (2013) | PBC (2010) | PBC (2002) | PBC (2013) | AIH (2008) | AIH (2008) | AIH (2017) | AIH (1994) |
| Liver biopsy | No | Yes | Yes | Yes | No | No | Yes | Yes |
| Liver enzymes | Normal | Hepatocellular | Cholestatic | Cholestatic | Cholestatic | Normal | Normal | Normal |
| SMA | − | − | − | − | positive | − | positive | − |
| M2/M4 | − | positive | − | positive | − | − | − | − |
| LKM | − | − | − | − | − | − | − | − |
| AMA‐M2 | ++ | +++ | +++ | +++ | − | − | − | − |
| 3E (BPO) | + | +++ | +++ | +++ | − | − | − | − |
| Sp100 | − | +++ | − | − | − | − | − | − |
| gp210 | +++ | − | − | − | − | − | − | − |
| SLA/LP | − | + | − | − | +++ | − | ++ | − |
| Ro52/SSA | + | +++ | − | +++ | + | +++ | − | +++ |
| IF‐ANA | AC‐4 | AC‐4 | AC‐3 | AC‐1+4 | AC‐4 | AC‐1 | AC‐1 | AC‐1+4 |
SLE = systemic lupus erythematosus; AILD = autoimmune liver disease; SMA = smooth muscle antibodies; LKM = liver kidney microsomal antigen; AMA = anti‐mitochondrial antibodies; SLA/LP = soluble liver antigen/liver pancreas antigen; ANA = anti‐nuclear antibodies; PBC = primary biliary cholangitis; AIH = autoimmune hepatitis.