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. 2020 Dec 16;10:22090. doi: 10.1038/s41598-020-78993-w

Table 2.

Associations of AGEs with patient characteristics.

PEN (pmol/mgCre, log) CML (µg/mL, log)
Correlation coefficient P value Correlation coefficient P value
Age, years 0.230 < 0.001 0.212 < 0.001
Body height, cm − 0.138 < 0.01 − 0.145 < 0.01
Body weight, kg 0.053 0.27 − 0.041 0.39
Trunk circumference, cm 0.156 < 0.01 0.077 0.11
Trunk fat, % 0.031 0.52 0.059 0.22
Hip fat, % 0.024 0.61 0.117 < 0.05
Lumbar BMD, g/cm2 0.048 0.32 − 0.180 < 0.001
Hip BMD, g/cm2 − 0.017 0.72 − 0.072 0.13
Albumin, g/dL 0.016 0.74 − 0.100 < 0.05
BUN, mg/dL 0.064 0.19 0.131 < 0.01
Creatinine, mg/dL 0.078 0.099 0.030 0.54
Uric acid, mg/dL 0.134 < 0.01 0.018 0.71
eGFR, mL/min/1.73m2 − 0.097 < 0.05 − 0.080 0.094
Total cholesterol, mg/dL − 0.061 0.20 0.064 0.18
Triglycerides, mg/dL 0.014 0.78 0.044 0.36
HbA1c, % 0.146 < 0.01 0.171 < 0.001
Homocysteine, nmol/mL, log 0.160 < 0.001 0.019 0.69
NTx, nmolBCE/mmolCre, log 0.145 < 0.01 − 0.014 0.77
Osteocalcin, ng/mL, log − 0.044 0.38 0.048 0.34
Sclerostin, pmol/L, log 0.079 0.12 0.132 < 0.01
FGF23, pg/mL, log 0.062 0.22 0.105 < 0.05
Leptin, ng/mL, log 0.015 0.77 0.046 0.36
Adiponectin, µg/mL, log 0.063 0.21 0.045 0.38

AGEs advanced glycation end products, PEN pentosidine, CML carboxymethyl-lysine, BMD bone mineral density, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, NTx cross-linked N-telopeptide of type I collagen, FGF23 fibroblast growth factor 23.