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. 2020 Dec 16;11:6398. doi: 10.1038/s41467-020-19814-6

Fig. 1. Manhattan plot depicting loci associated with childhood asthma with severe exacerbations in the discovery genome-wide meta-analysis.

Fig. 1

Association P value (suggestive threshold line in black): 1 × 10−4, (genome-wide threshold line in red): 5.0 × 10−8. Associations are from fixed-effect meta-analyses based on logistic regression models adjusted for sex and the first ten principal components. Ndiscovery = 68,281 individuals (NCOPSACsevere = 6532 and NiPSYCH = 61,749).