Table 1.
Clinical, radiological, and microbiological characteristics of patients and treatment received during ICU stay.
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| Age (years) | 72 | 68 | 59 |
| Gender | Male | Male | Male |
| Known comorbidities | Hypertension | Hypertension | Hypertension |
| Hyperthyroidism | |||
| Benign hypertrophy of the prostate | Dyslipidemia | ||
| Symptoms | Fever 38.7°C | Fever 38.9°C | Fever 38.5°C |
| Dry cough | Dry cough | Dry cough | |
| Shortness of breath | Shortness of breath | Anosmia | |
| Thoracic pain | Fatigue | ||
| Symptom duration before admission (days) | 13 | 7 | 10 |
| Admission to death (days) | 15 | 5 | 9 |
| Physical examination in admission | RR = 33 cpm | RR = 36 cpm | RR = 34 cpm |
| SpO2 = 73% | SpO2 = 84% | SpO2 = 83% | |
| HR = 95 bpm | HR = 95 cpm | HR = 88 cpm | |
| BP: 110/60 mmHg | BP = 120/60 mmHg | BP = 130/80 mmHg | |
| Blood sugar: 1.44 g/L | Blood sugar: 1.7 g/L | Blood sugar: 3.5 g/L | |
| Thoracic CT scan | Ground glass | Ground glass > 75% | Ground glass > 80% |
| Crazy paving > 70% | |||
| Blood culture | Multiresistant | Sterile | Sterile |
| Acinetobacter baumannii | |||
| Gram-positive bacteria sensitive to colistin (catheter related infection) | |||
| Duration of ventilator management (days) | CPAP = 10 | CPAP = 3 | CPAP = 6 |
| IV = 5 | IV = 2 | IV = 3 | |
| Treatment | Hydroxychloroquine | ||
| Antibiotics | |||
| Therapeutic dose of LMWH | |||
| Acetylsalicylic acid | |||
| Methylprednisolone | |||
| Zinc | |||
| Vitamin C | |||
| Acetaminophen | |||
| Carbimazole | |||
| Tocilizumab | |||
| Blood type | O+ | A+ | A+ |
| Microbiology (lung tissue and pleural fluid) | Negative | Negative | Negative |
| SARS-CoV-2 on pleural fluid | Negative | Positive | Positive |
| SARS-CoV-2 on lung biopsy | Negative | Positive | Positive |
RR: respiratory rate; HR: heart rate; SpO2: pulsed oxygenation saturation; BP: blood pressure; CPAP: continuous positive airway pressure; IV: invasive ventilation.