TABLE 1.

Univariate Cox regression analysis of all clinical indicators and the five-gene risk group.

Clinical indicator	Beta	HR	95% CI for HR	Wald.test	P value
PROT	−0.21	0.81	0.57–1.2	1.2	0.27
AGE	0.025	1	1–1	8.8	0.0029*
SEX	−0.05	0.95	0.7–1.3	0.1	0.75
RACE	0.041	1	0.65–1.7	0.03	0.86
ISOTYPE	−0.01	0.99	0.88–1.1	0.03	0.87
B2M	0.73	2.1	1.4–3.1	12	0.00051*
CRP	0.33	1.4	1–1.9	4.1	0.044*
CREAT	0.5	1.6	1.2–2.3	9.4	0.0021*
LDH	0.0063	1	1–1	51	9.60E-13*
ALB	−0.71	0.49	0.35–0.7	16	7.00E-05*
HGB	−0.38	0.68	0.49–0.95	5.3	0.022*
ASPC	0.01	1	1–1	10	0.0015*
BMPC	0.0094	1	1–1	10	0.0016*
MRI	0.017	1	1–1	14	0.00016*
CPS1	−0.05	0.95	0.7–1.3	0.1	0.75
CPR1	−0.23	0.79	0.58–1.1	2.2	0.13
Cyto_Abn	0.82	2.3	1.7–3.1	28	1.10E-07*
Riskgroup	1.2	3.2	2.3–4.6	45	2.10E-11*

HR, hazard ratio; CI, confidence interval; and *p < 0.05.