TABLE 2.

Multivariate Cox regression analysis of eleven clinical indicators and the five-gene risk group.

Clinical indicator	Beta	HR	95% CI for HR	P value
AGE	0.013074	1.01316	0.9948–1.0319	0.16138
B2M	0.001555	1.001556	0.9951–1.0080	0.636028
CRP	–0.002855	0.997149	0.9895–1.0048	0.466398
CREAT	0.15395	1.166433	1.0626–1.2804	0.001208*
LDH	0.003973	1.003981	1.0018–1.0061	0.000255*
ALB	–0.430165	0.650402	0.4894–0.8644	0.003035*
HGB	–0.005505	0.99451	0.8929–1.1076	0.920218
ASPC	0.000926	1.000927	0.9911–1.0109	0.85443
BMPC	0.001769	1.00177	0.9922–1.0115	0.718921
MRI	0.011171	1.011233	1.0011–1.0214	0.029327*
Cyto_Abn	0.525037	1.690522	1.2046–2.3725	0.002393*
Riskgroup	0.780364	2.182267	1.4950–3.1855	5.26E-05*

HR, hazard ratio; CI, confidence interval; *p < 0.05.

Concordance-index = 0.741 (se = 0.021).

Likelihood ratio test = 108.3, p = < 2e-16.

Wald test = 114.5, p = < 2e-16.

Score (logrank) test = 129.4, p = < 2e-16.