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. 2020 Dec 3;11:600767. doi: 10.3389/fphys.2020.600767

TABLE 1.

Enriched cellular markers of transcriptionally-defined subpopulations of brain vascular cells.

Cardinal cell identity Sub-stratification Selected enriched markers References
Endothelial Arterial Gkn3, Hey1, Bmx, Efnb2, Vegfc, Sema3g, Mgp, Fbln2, Fbln5, Cytl1 Tm4sf1 Sabbagh et al., 2018; Saunders et al., 2018; Vanlandewijck et al., 2018; Zeisel et al., 2018; Kalucka et al., 2020
Capillary Mfsd2a, Tfrc, Meox1, Rgcc Sabbagh et al., 2018; Saunders et al., 2018; Vanlandewijck et al., 2018; Zeisel et al., 2018; Kalucka et al., 2020
Venous Slc38a5, Nr2f2, Lcn2, Ccl19, Mafb, Mmm 1, Vwf Sabbagh et al., 2018; Saunders et al., 2018; Vanlandewijck et al., 2018; Zeisel et al., 2018; Kalucka et al., 2020
Tip Cells Plaur, Angpt2, Lcp2, Cxcr4, Apln, Kcne3, Mcam, Lamb1, Trp53i11 Sabbagh et al., 2018
Choroid plexus Plvap, Plpp3, Esm1, Plpp1, Cd24a, Nrp1, Rgcc Kalucka et al., 2020
Pericytes Abcc9, Kcnj8, Vtn, Ifitm1, Ggt1 Saunders et al., 2018; Vanlandewijck et al., 2018; Zeisel et al., 2018
Vascular smooth muscle cells Arterial Acta, Tagln, Cnn1, Tinagl1, Fos Saunders et al., 2018; Vanlandewijck et al., 2018
Venous Kcnj8, Abcc9, Car4, Slc5a5 Saunders et al., 2018; Vanlandewijck et al., 2018
Fibroblasts Perivascular Col1a1, Col1a2, Lum, Dcn, Pdgfra Saunders et al., 2018; Vanlandewijck et al., 2018;
Pial S100a6, Col18a1, Postn, Lama2, Ngfr DeSisto et al., 2020
Arachnoid Ptgds, Aldh1a2, Crabp2, Ogn DeSisto et al., 2020
Dura Alpl, Foxc2, Fxyd5, Dkk2, Mgp, Crabp2 DeSisto et al., 2020
Perivascular macrophages Mrc, Lyve1, Lyl1, Spic Zeisel et al., 2015