Figure 6.

CK2α Interference Decreased the Promotion of Cell Proliferation Induced by ALKBH5 in Bladder Cancer Cells

(A) CCK-8 assays were used to measure the effect of siCK2α or SCR on 5637 and T24 cells with ALKBH5 knockdown. siCK2α could partly reduce cell growth induced by knockdown of ALKBH5 in 5637 and T24 cells. (B) Colony-formation assays showed that siCK2α could rescue the cell growth promoted by knockdown of ALKBH5 in 5637 and T24 cells. (C–E) siCK2α decreased glucose uptake, lactic acid production, and ATP production of bladder cancer cells within 24 h. Data represent the mean ± SD from three independent experiments, ∗p < 0.05