Fig. 4.

Construction of gene vectors with high transfection efficiency and low cytotoxicity. (A) Aspect ratio-controlled (modulating PEG crowdedness) polyplex formation with multi-arm PEG-PLL. Reproduced with permission from Ref. [112], copyright 2019, American Chemical Society. (B) Introducing multiple interactions and α-helix conformation into PLL-based polycations via the incorporation of an RT ring in PLL. Reproduced with permission from Ref. [113], copyright 2018, American Chemical Society.