Figure 1.

Upregulated and downregulated DEG distribution in HCC samples based on the GSE22058 and GSE54238 datasets. (A, B) DEG hierarchical clustering analysis. All the data input represents the log₂ ratio of HCC intensity relative to the normal intensity. The red color represents markedly upregulated genes selected at p <0.05; the blue color represents markedly downregulated genes at p <0.05. (C, D) PCA was performed to separate HCC from nontumor samples. aHCC, advanced hepatocellular carcinoma.