Fig. 3.

Pancreatic Nrf2a expression and protein glutathionylation patterns in response to tBOOH exposure. (A) Exposure paradigm. (B) Potential mechanism for tBOOH-mediated changes in Nrf2a and protein glutathionylation. (C) Nrf2a and protein glutathionylation patterns in pancreata of fish exposed to stated treatments. Solid lines denote exocrine pancreas, dashed lines denote endocrine pancreas; representative images from 10 to 14 fish. Scale bars represent 20 μm. Grayscale split channel images of the Nrf2a immunohistochemistry are provided in Supplementary Fig. 2, and BioGEE immunohistochemistry in Supplementary Fig. 3.