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. 2020 Dec 16;10:22023. doi: 10.1038/s41598-020-79146-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in physiologic parameters and urine-protein by administration of deferasirox. Body weight (a), Systolic blood pressure (b), Urine volume for 24 h (c), and Urine-protein for 24 h (d) in the control (n = 6), the HS (n = 6) and the HSDFX (n = 4) groups. Statistical analysis for each time-point was performed using one-way analysis of variance followed by Tukey–Kramer test in (a), (b), (c), and (d) by JMP Pro Version 14.2.0 software (SAS Institute Inc.). *p < 0.05 vs. the control group.