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. 2020 Dec 16;10:22023. doi: 10.1038/s41598-020-79146-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Histological analysis of kidney in Dahl/SS rats. (a) Representative PAS staining of the renal cortex in the control, the HS and the HSDFX groups (bars 100 μm). (b) Representative Berlin blue staining of the renal cortex in the control, the HS and the HSDFX groups (bars 100 μm). As histological analysis of kidney, tubulointerstitial lesion score (c), glomerular sclerosis score (d), tubular injury score in the medullary rays (e) and the inner stripe (f), and arterial injury score (g) are shown. Statistical analysis was performed using one-way analysis of variance followed by Tukey–Kramer test in (c), (d), (e), (f), and (g) by JMP Pro Version 14.2.0 software (SAS Institute Inc.). *p < 0.05 vs. the control group, ^†p < 0.05 vs. the HS group.