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. 2020 Dec 3;7:581763. doi: 10.3389/fmed.2020.581763

Table 4.

Univariable-adjusted and multivariable-adjusted odds ratios of chronic obstructive pulmonary disease associated with risk factors.

Variables Univariable-adjusted Multivariable-adjusted
OR (95% CI) P-value OR (95% CI) P-value
Male gender 1.12 (0.91–1.39) 0.275 1.25 (0.96–1.62) 0.095
Age, years
   15–39 1.00 (Reference) 1.00 (Reference)
   ≥40 3.03 (2.40–3.82) <0.0001 2.25 (1.72–2.95) <0.0001
Altitude,m
   2,100–3,000 1.00 (Reference) 1.00 (Reference)
   3,000–4,000 0.57 (0.44–0.73) <0.0001 0.61 (0.46–0.79) <0.0001
   >4,000 0.46 (0.35–0.62) <0.0001 0.45 (0.33–0.61) <0.0001
Education level
   Primary school and lower 1.00 (Reference) 1.00 (Reference)
   Middle and high school 0.38 (0.28–0.52) <0.0001 0.49 (0.35–0.68)   <0.0001
   College and higher 0.38 (0.27–0.53) <0.0001 0.64 (0.43–0.95) 0.025
Pack–years of smoking
   0 1.00 (Reference) 1.00 (Reference)
   1–19 0.87 (0.42–1.80) 0.714 1.22 (0.58–2.57) 0.609
   ≥20 1.49 (1.18–1.88) 0.001 1.21 (0.91–1.60) 0.191
Household air pollution 1.82 (1.42–2.40) <0.0001 1.34 (1.01–1.79) 0.043
History of tuberculosis 2.28 (1.58–3.29) <0.0001 1.79 (1.23–2.61) 0.030
Exposure to dust or chemicals in the workplace 1.56 (0.90–2.70) 0.108 1.19 (0.67–2.10) 0.558