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. 2020 Dec 3;12:576682. doi: 10.3389/fnagi.2020.576682

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Copyright © 2020 Wang, Liu, Ruan, Li, Li, Zhang, Li and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ANOVA within the bilateral caudate/putamen. (A) Group effect [GRF corrected, voxel p < 0.05, cluster p < 0.05, threshold of t > 2.00, and cluster size >69 voxels (1,863 mm³)]. (B) Frequency effect [GRF corrected, voxel p < 0.05, cluster p < 0.05, threshold of t > 2.00, and cluster size >50 voxels (1,350 mm³)]. (C) ALFF of two groups within the significant region of group effect, the left caudate/putamen. (D) Clinical correlations within the significant region of group effect (the left caudate/putamen) (FDR corrected, p < 0.05). L/R, left/right; LEDD, levodopa equivalent daily dose; HY, Hoehn and Yahr scale. **p < 0.001, ***p < 0.0001.