Table 1.
Characteristics of Youth Living With Perinatally Acquired Human Immunodeficiency Virus and Youth Without Human Immunodeficiency Virus
| YLPHIV (n = 431) | Youth Without HIV (n = 93) | P | |||
|---|---|---|---|---|---|
| n | Values | n | Values | ||
| Demographics | |||||
| Age,a years | 431 | 14.1 (12.8, 15.5) | 93 | 13.9 (12.1, 15.3) | .21 |
| Femaleb | 431 | 213 (49.4) | 93 | 53 (57.0) | .19 |
| Tobacco use in last 12 monthsb | 427 | 9 (2.1) | 92 | 2 (2.2) | .97 |
| Growth measures | |||||
| Height-for-age z scorea | 422 | −1.25 (−2.03, −0.55) | 89 | −0.74 (−1.37, 0.06) | <.01 |
| Weight-for-age z scorea | 429 | −0.83 (−1.63, −0.03) | 92 | −0.13 (−0.83, 0.75) | <.01 |
| BMI-for-age z scorea | 421 | −0.21 (−0.95, 0.58) | 89 | 0.39 (−0.56, 1.26) | <.01 |
| Waist circumference,a cm | 428 | 66 (62, 70) | 91 | 69 (62, 76) | .02 |
| Hip circumference,a cm | 427 | 76 (71, 83) | 92 | 84.5 (73.5, 91.5) | <.01 |
| Mid-thigh circumference,a cm | 425 | 39 (36, 42) | 92 | 43 (38, 47) | <.01 |
| Midupper arm circumference,a cm | 429 | 22 (20, 24) | 91 | 23 (21, 26) | <.01 |
| Waist to hip ratiob | |||||
| Female | 211 | 0.84 (0.80, 0.89) | 51 | 0.82 (0.78, 0.87) | .01 |
| Male | 216 | 0.89 (0.86, 0.92) | 40 | 0.85 (0.82, 0.89) | <.01 |
| Blood pressure,a mmHg | |||||
| Systolic | 431 | 104 (97, 111) | 93 | 107.5 (103, 115) | <.01 |
| Diastolic | 431 | 67 (61, 71) | 93 | 69.5 (64, 73.5) | .01 |
| Elevated blood pressureb | 431 | 93 | |||
| Normal | 366 (84.9) | 75 (80.7) | .306 | ||
| High | 65 (15.1) | 18 (19.4) | |||
| Tanner stageb | 416 | 91 | |||
| 1 | 63 (15.1) | 12 (13.2) | .75 | ||
| 2 | 78 (18.8) | 16 (17.6) | |||
| 3 | 87 (20.9) | 25 (27.5) | |||
| 4 | 103 (24.8) | 21 (23.1) | |||
| 5 | 85 (20.4) | 17 (18.7) | |||
| Laboratory measures | |||||
| hs-CRP,a mg/L | 422 | 1.09 (0.5, 3.5) | 91 | 0.69 (0.3, 2.1) | .01 |
| Triglycerides,a mmol/L | 417 | 0.9 (0.7, 1.2) | 88 | 0.6 (0.5, 0.8) | <.01 |
| Hypertriglyceridemiab | 54 (17.3) | 1 (1.9) | <.01 | ||
| Total cholesterol,a mmol/L | 417 | 4.0 (3.5, 4.7) | 89 | 3.5 (3.2, 4.1) | <.01 |
| Hypercholesterolemiab | 42 (10.1) | 1 (1.1) | .01 | ||
| LDL,a mmol/L | 417 | 2.1 (1.8, 2.7) | 87 | 1.9 (1.5, 2.2) | .01 |
| High LDLb | 14 (4.5) | 1 (1.9) | .39 | ||
| HDL,a mmol/L | 417 | 1.4 (1.2, 1.7) | 89 | 1.3 (1.1, 1.7) | .16 |
| Low HDLb | 35 (8.4) | 9 (10.1) | .60 |
All continuous variables are expressed as medians (interquartile range) or means (SD) and categorical variables as n (%).
Abbreviations: BMI, body mass index; HDL, high-density-lipoprotein cholesterol; HIV, human immunodeficiency virus; hs-CRP, highly sensitive C-reactive protein; LDL, low-density-lipoprotein cholesterol; YLPHIV, youth living with perinatally acquired HIV.
aContinuous variable.
bCategorical variable.