Table 4.
Regression Model Evaluating the Unadjusted and Adjusted Association Between Perinatally Acquired Human Immunodeficiency Virus Infection and Endothelial Dysfunction
| Variable | Unadjusted Relative Risk (95% CI) | P | Adjusted Relative Risk (95% CI) | P |
|---|---|---|---|---|
| Youth without HIV | Ref | Ref | ||
| Perinatally acquired HIV infection | 1.44 (1.08, 1.95) | .01 | 1.43 (1.06, 1.95) | .02 |
| Age,a per 1-year increment | 0.83 (.78, .87) | <.01 | .81 (.77, .86) | <.01 |
| Gender | ||||
| Male | Ref | Ref | ||
| Female | 0.86 (.72, 1.03) | .10 | .90 (.75, 1.08) | .26 |
| Elevated BP | ||||
| Normal | Ref | Ref | ||
| High | 0.76 (.57, 1.02) | .07 | .70 (.51, .96) | .03 |
| BMI z score,a per 1-unit increase | 0.90 (.83, .97) | <.01 | .91 (.84, .99) | .03 |
| Total cholesterol | ||||
| Normal | Ref | Ref | ||
| High | 1.04 (.76, 1.44) | .78 | .87 (.64, 1.19) | .38 |
Abbreviations: BMI, body mass index; BP, blood pressure, CI, confidence interval; HIV, human immunodeficiency virus; Ref, reference.
aContinuous variable.