Table 2.

Differences in the loading coefficient of independent components.

Components	Healthy subjects	MDD patients	p-value	Cohen’s d
	Mean ± SD	Mean ± SD
Component 2	0.43 ± 0.54	0.08 ± 0.92	0.04	0.46
Component 3	− 0.28 ± 0.74	− 0.58 ± 0.81	0.09	0.38
Component 4 prefrontal network	0.24 ± 0.76	− 0.25 ± 0.71	< 0.01*	0.68
Component 5 insula-temporal network	0.39 ± 0.74	− 0.27 ± 0.80	< 0.01*	0.84
Component 6	− 0.19 ± 0.74	0.16 ± 0.74	0.04	0.47
Component 9	− 0.20 ± 0.87	− 0.05 ± 0.93	0.46	0.17
Component 10	− 0.05 ± 0.84	− 0.3 ± 0.95	0.21	0.28
Component 11	0.11 ± 0.80	− 0.18 ± 0.72	0.09	0.38
Component 12	− 0.04 ± 0.78	− 0.26 ± 0.85	0.24	0.26
Component 14	− 0.23 ± 0.99	− 0.41 ± 0.86	0.39	0.19

SD, standard deviation, MDD, Major depression disorders.

*Significant difference after Bonferroni correction.