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. 2020 Dec 16;10:22097. doi: 10.1038/s41598-020-78366-3

Figure 2.

Figure 2

RNA-Sequencing analysis defines clone types upon in vitro expansion of human Adult Kidney single cell derived clones. (A) Euclidean distance analysis was performed on RNAseq data to illustrate variation in transcription levels between samples. FLCs are more similar to late BAK than to ELCs while early and late ELCs are clustered together. The distance between cell types is demonstrated by a heatmap. Darker color indicates lesser distance which means greater similarity; (B) Principal component analysis was performed on RNA-Seq data to illustrate variation in transcription levels between samples. Different colors denote culture type. Different shapes denote early or late passage. Bulk Human Adult Kidney-BAK; FLC-Fibroblast-Like Clones; ELC-Epithelial-Like Clones.