Table 3.
ROC analysis, sensibility and specificity of candidate genes to predict TB reactivation.
Gene | ROC AUC (95% CI) | ROC p-value | Sensitivity % (95% CI) | Specificity % (95% CI) | Cut-off |
---|---|---|---|---|---|
C1QB | 0.97 (0.92–1.02) | 0.0003360 | 88.24 (63.56–98.54) | 100 (59.04–100) | > 4.15 |
C2 | 0.92 (0.82–1.02) | 0.001348 | 82.35(56.57–100) | 100 (59.04–100) | > 4.16 |
CCR2 | 1.00 | 0.0001594 | 100 (80.49–100) | 100 (59.04–100) | > 8.61 |
CCRL2 | 0.86 (0.71–1.01) | 0.005753 | 82.35 (56.57–96.20) | 85.71 (42.13–99.64) | > 5.31 |
LILRB4 | 0.94 (0.82–1.05) | 0.0008613 | 94.12 (71.31–99.85) | 100 (59.04–100) | > 6.56 |
MAPK14 | 0.95 (0.88–1.03) | 0.0005420 | 88.24 (63.56–98.54) | 100 (59.04–100) | > 10.54 |
MSR1 | 0.99 (0.96–1.01) | 0.0002051 | 94.12 (71.31–99.85) | 100 (59.04–100) | > 4.72 |