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. 2020 Dec 16;10:22072. doi: 10.1038/s41598-020-78793-2

Table 3.

ROC analysis, sensibility and specificity of candidate genes to predict TB reactivation.

Gene ROC AUC (95% CI) ROC p-value Sensitivity % (95% CI) Specificity % (95% CI) Cut-off
C1QB 0.97 (0.92–1.02) 0.0003360 88.24 (63.56–98.54) 100 (59.04–100) > 4.15
C2 0.92 (0.82–1.02) 0.001348 82.35(56.57–100) 100 (59.04–100) > 4.16
CCR2 1.00 0.0001594 100 (80.49–100) 100 (59.04–100) > 8.61
CCRL2 0.86 (0.71–1.01) 0.005753 82.35 (56.57–96.20) 85.71 (42.13–99.64) > 5.31
LILRB4 0.94 (0.82–1.05) 0.0008613 94.12 (71.31–99.85) 100 (59.04–100) > 6.56
MAPK14 0.95 (0.88–1.03) 0.0005420 88.24 (63.56–98.54) 100 (59.04–100) > 10.54
MSR1 0.99 (0.96–1.01) 0.0002051 94.12 (71.31–99.85) 100 (59.04–100) > 4.72