Table 2.

Curated functional hierarchy tree of Mesoplasma florum annotated ORFs.

Functional category	Subcategory	Sub subcategory	Number of ORFs	% of total ORFs
Cellular processes	Cytoskeleton	Cytoskeleton proteins	2	0.3
Environmental information processing	Signal transduction	Two‐component system	1	0.1
Genetic information processing	DNA maintenance	DNA repair	23	3.4
		DNA replication and partition	30	4.4
		Subtotal	53	7.7
	Folding, sorting and degradation	Chaperones and folding catalysts	7	1.0
		Nucleases	11	1.6
		Peptidases	9	1.3
		Protein export	7	1.0
		Sulfur relay system	2	0.3
		Subtotal	36	5.3
	Transcription	RNA polymerase	5	0.7
		Transcription factors	6	0.9
		Subtotal	11	1.6
	Translation	Ribosome	51	7.4
		Ribosome biogenesis	29	4.2
		Translation factors	11	1.6
		tRNA loading and maturation	30	4.4
		Subtotal	121	17.7
	Total		221	32.3
Metabolism	Biosynthesis	Amino acid metabolism	5	0.7
		Cofactor biosynthesis	16	2.3
		Lipid and steroid metabolism	8	1.2
		Purine and pyrimidine metabolism	23	3.4
		Subtotal	52	7.6
	Central carbon metabolism	Glycolysis and carbohydrate metabolism	35	5.1
		Other central metabolism enzymes	6	0.9
		Pentose phosphate metabolism	8	1.2
		Subtotal	49	7.2
	Energy metabolism	Oxidative phosphorylation	9	1.3
	Membrane transport	PTS system	13	1.9
		Secretion system	2	0.3
		Transport	42	6.1
		Subtotal	57	8.3
	Other enzymes	Other enzymes	22	3.2
	Total		189	27.6
Not mapped	–	–	250	36.5
Unclear	–	–	22	3.2
Grand total			685	100.0