Fig. 3.

Profile of KCO effects on rhythmic contractions and intraluminal flow of isolated mesenteric LVs. Increasing concentrations of KCOs: cromakalim (○), minoxidil sulfate (▪), and diazoxide (∆) significantly decreased the amplitude of contraction (A), progressively reduced the frequency of contraction (B), resulted in a small but significant increase in EDD (C), and decreased calculated lymph flow (D). Data are reported as mean ± S.D. analyzed using one-way ANOVA with Holm-Sidak post-test, significance refers to ANOVA. (n = 6, **P < 0.01; ****P < 0.0001).