Fig. 4.

Cromakalim and minoxidil sulfate decrease lymph flow in vivo. Bathing the mesentery with HEPES-PSS (□) did not significantly affect lymph flow, although there was a trend of increasing lymph flow during the experiment. Increasing concentrations of cromakalim (▪) and minoxidil sulfate (▪) significantly decreased lymph flow compared with HEPES-PSS controls. Data reported as mean ± S.D. analyzed using one-way ANOVA with Holm-Sidak post-test (n = 5, *P < 0.01; ****P < 0.0001). Significance reported over bars indicates significance compared with baseline. Significance denoted with labels indicates one-way ANOVA significance.