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(A) In vitro cell cytotoxicity of different drug formulations against RAW 264.7 cells after 72 h incubation. Values were expressed as mean ± SD (n = 6). (B) Quantitative analysis of average TRAP positive cells per representative view. ∗∗∗P < 0.001. (C) Representative microscopy images of osteoclasts differentiation stimulated by RANKL (50 ng/mL) containing different drug formulations. Osteoclasts were stained in purple. Scale bar: 50 μm.
