Table 1.
Comparisons of demographics and baseline characteristics of patients separated into high- and low trajectories (all patients)
| Demographic | High trajectory (n = 1471) | Low trajectory (n = 1539) | P |
|---|---|---|---|
| Age, years: mean (s.d.) | 31.28 (8.29) | 31.56 (8.23) | 0.361 |
| Gender male, n (%) | 718 (48.8) | 754 (49.0) | 0.228 |
| First-onset psychosis, n (%) | 444 (30.2) | 421 (27.4) | 0.094 |
| Education, n (%) | 0.002 | ||
| Doctor | 2 (0.1) | 1 (0.1) | |
| Master | 8 (0.5) | 5 (0.3) | |
| Bachelor | 108 (7.3) | 135 (8.8) | |
| College | 134 (9.1) | 166 (10.8) | |
| High school | 350 (23.8) | 428 (27.8) | |
| Middle school | 578 (39.3) | 576 (37.4) | |
| Primary school | 269 (18.3) | 217 (14.1) | |
| Illiterate | 22 (1.5) | 11 (0.7) | |
| Body mass index (kg/m2), mean (s.d.) | 21.87 (5.78) | 21.90 (7.92) | 0.919 |
| Age of onset, years: mean (s.d.) | 25.84 (7.26) | 24.71 (6.62) | <0.001 |
| Illness duration, months: mean (s.d.) | 66.45 (66.63) | 84.11 (73.10) | <0.001 |
| Family history, n (%) | 303 (20.6) | 338 (22.0) | 0.385 |
| Doses,a mg: mean (s.d.) | 7.17 (3.03) | 7.44 (2.83) | 0.011 |
| PANSS Total, mean (s.d.) | 89.46 (16.11) | 89.38 (14.51) | 0.888 |
| PANSS% change (week 2), mean (s.d.) | 35.84 (16.68) | 15.16 (12.48) | <0.001 |
| PANSS% change (week 4), mean (s.d.) | 60.51 (15.34) | 28.10 (15.31) | <0.001 |
| PANSS% change (week 6), mean (s.d.) | 73.58 (13.54) | 31.99 (19.62) | <0.001 |
PANSS, Positive and Negative Syndrome Scale.
a.
The drug doses was converted into risperidone doses by daily defined dose.