表 1.
颈椎失稳及非颈椎失稳RA患者临床特征的比较
Comparison of clinical characteristics of RA patients with cervical spine instability and none cervical spine instability
| Items | Cervical spine instability group (n=130) | None cervical spine instability group (n=309) | P |
| VAS, visual analogue scale; DAS28-ESR, 28-joint disease activity score-erythrocyte sedimentation rate; CCP, cyclic-citrullinated peptide; RF, rheumatoid factor; AKA, anti-keratin antibody; ANA, anti-nuclear antibody; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; WBC, white blood cell; HGB, hemoglobin; PLT, blood platelet; cDMARDs, conventional disease modifying anti-rheumatic drugs; bDMARDs, biological disease modifying anti-rheumatic drugs. | |||
| Female，n(%) | 107 (82.3) | 248 (80.3) | 0.816 |
| Age/years, x±s | 52.03±13.76 | 53.33±13.94 | 0.624 |
| Duration of disease/months, M(P25, P75) | 120 (36, 240) | 48 (12, 120) | < 0.001 |
| Swollen joints, M(P25, P75) | 3 (1, 9) | 2 (0, 8) | 0.237 |
| Tender joints, M(P25, P75) | 5 (1, 13) | 4 (1, 12) | 0.575 |
| Peripheral joint malformations, n(%) | 74 (56.9) | 92 (29.9) | < 0.001 |
| VAS measuring general health score, x±s | 4.89±2.49 | 3.93±2.38 | < 0.001 |
| DAS28-ESR score, M(P25, P75) | 4.89 (3.46, 6.14) | 4.38 (3.03, 5.90) | 0.099 |
| Anti-CCP positive, n(%) | 108 (90.8) | 226 (76.6) | 0.001 |
| RF positive, n(%) | 101 (80.8) | 226 (75.1) | 0.203 |
| AKA positive, n(%) | 17 (15.3) | 34 (12.5) | 0.454 |
| ANA positive, n(%) | 65 (53.7) | 146 (51.4) | 0.670 |
| High CRP levels, n(%) | 85 (68.5) | 187 (63.8) | 0.354 |
| ESR/(mm/H)，M(P25, P75) | 30.0 (16.0, 58.0) | 30.0 (16.0, 57.3) | 0.374 |
| WBC/(×109/L), x±s | 6.30±2.36 | 6.54±2.43 | 0.439 |
| HGB/(g/L)，x±s | 111.31±19.44 | 115.56±16.60 | 0.021 |
| PLT(×109/L), x±s | 280.94±103.61 | 284.14±95.77 | 0.987 |
| Glucocorticoids usage longer than 6 months, n(%) | 75 (59.5) | 148 (50.7) | 0.096 |
| cDMARDs usage more the 3 months, n(%) | 91 (73.4) | 212 (74.1) | 0.876 |
| bDMARDs usage, n(%) | 110 (86.6) | 268 (89.3) | 0.420 |