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. 2020 Oct 19;52(6):1040–1047. [Article in Chinese] doi: 10.19723/j.issn.1671-167X.2020.06.009

表 3.

EORA合并CVD与不合并CVD临床特征的差异

Clinical characteristics of EORA patients with or without CVD

Items CVD (n=59) Without CVD (n=153) Z/χ2 P value
  Data are presented as n (%) or median (P25, P75). Abbreviations as in Table 1 and Table 2.
Male 22 (37.3) 46 (30.1) 1.02 0.313
Age/years 74 (70, 78) 70 (67, 75) -3.12 0.002
Disease duration/years 4 (1, 8) 2 (1, 5) -1.83 0.068
SJCs 3 (1, 8) 4 (1, 10) -0.50 0.620
TJCs 6 (2, 15) 6 (2, 17) -0.77 0.444
DJCs 28 (47.5) 51 (33.3) 3.63 0.057
ESR/(mm/h) 47 (30, 65) 43 (23, 71) -0.36 0.716
CRP/(mg/L) 10.4 (2.8, 37.7) 14.0 (1.8, 46.7) -0.77 0.442
DAS28-ESR 4.6 (3.7, 5.7) 4.5 (3.7, 5.8) -0.47 0.636
  ≤2.6 6 (8.5) 10 (6.5) 0.81 0.369
  >2.6, ≤3.2 4 (6.8) 11 (7.2) 0.01 >0.999
  >3.2, ≤5.1 29 (49.2) 75 (49.0) 0.00 0.986
  >5.1 20 (33.9) 57 (37.3) 0.21 0.649
Rheumatoid factor (positive) 14/49 (28.6) 11/121 (9.1) 10.55 0.001
Anti-CCP antibody (positive) 10/30 (33.3) 13/79 (16.5) 3.72 0.054
Extra-articular manifestations
  Interstitial lung disease 16 (27.1) 34 (22.2) 0.57 0.452
  Pleural effusion 2 (3.4) 1 (0.6) 2.29 0.188
  Pericardial effusion 1 (1.7) 0 (0) 2.606 0.278
  Rheumatoid nodules 7 (11.9) 6 (3.9) 4.67 0.050
  Cutaneous vasculitis 0 (0) 1 (0.6) 0.387 >0.999
  Anemia 10 (16.9) 24 (15.7) 0.050 0.822
  Peri-neuropathy 0 (0) 1 (0.6) 0.387 >0.999
  Sjögren's syndrome 4 (6.8) 7 (4.6) 0.421 0.503
Medications
  Non-DMARDs 16 (27.1) 59 (38.6) 2.44 0.118
  Methotrexate 9 (15.3) 54 (35.3) 10.09 0.004
  Hydroxychloroquine 4 (6.8) 35 (22.9) 7.35 0.007
  Leflunomide 25 (42.4) 61 (39.9) 0.11 0.739
  Sulfasalazine 9 (15.3) 40 (26.1) 2.84 0.092
  Prednisone 18 (3.1) 32 (20.9) 2.17 0.140
  Celecoxib 2 (3.3) 7 (4.6) 0.15 0.701
  Biological agents 3 (5.1) 17 (11.1) 1.81 0.179