表 2.
肌炎抗体在CADM与DM中分布的比较
Comparison of distribution of myositis autoantibodies between CADM and DM
| Items | CADM (n=89) | DM (n=130) | Comparison by overall positive rate | Comparison by titers | |||||||||||
| Overall | + | ++ | +++ | Overall | + | ++ | +++ | χ2 | P | χ2 | P | ||||
| Values are displayed as n(%). CADM，clinically amyopathic dermatomyositis; DM，dermatomyositis. | |||||||||||||||
| Myositis specific autoantibodies (MSAs) | |||||||||||||||
| Mi-2α | 1 (1.1) | 1 (1.1) | 0 | 0 | 7 (5.4) | 3 (2.3) | 3 (2.3) | 1 (0.8) | - | 0.146 | 3.124 | 0.077 | |||
| Mi-2β | 4 (4.5) | 3 (3.4) | 0 | 1 (1.1) | 6 (4.6) | 3 (2.3) | 3 (2.3) | 0 | - | 1 | 0.001 | 0.970 | |||
| TIF-1γ | 9 (10.1) | 8 (9.0) | 1 (1.1) | 0 | 15 (11.5) | 3 (2.3) | 5 (3.8) | 9 (6.9) | 0.444 | 0.505 | 4.202 | 0.040 | |||
| MDA5 | 32 (36.0) | 6 (6.7) | 6 (6.7) | 20 (22.5) | 15 (11.5) | 5 (3.8) | 2 (1.5) | 8 (6.2) | 20.65 | < 0.001 | 18.697 | < 0.001 | |||
| NXP2 | 5 (5.6) | 2 (2.2) | 1 (1.1) | 2 (2.2) | 7 (5.4) | 1 (0.8) | 3 (2.3) | 3 (2.3) | 0.006 | 0.941 | 0.022 | 0.883 | |||
| SAE1 | 3 (3.4) | 0 | 0 | 3 (3.4) | 1 (0.8) | 0 | 0 | 1 (0.8) | - | 0.306 | - | 0.306 | |||
| SRP | 4 (4.5) | 4 (4.5) | 0 | 0 | 8 (6.2) | 2 (1.5) | 2 (1.5) | 4 (3.1) | - | 0.765 | 2.108 | 0.147 | |||
| Jo-1 | 7 (7.9) | 2 (2.2) | 2 (2.2) | 3 (3.4) | 25 (19.2) | 2 (1.5) | 3 (2.3) | 20 (15.4) | 5.47 | 0.019 | 7.255 | 0.007 | |||
| PL-7 | 10 (11.2) | 5 (5.6) | 3 (3.4) | 2 (2.25) | 10 (7.7) | 2 (1.5) | 4 (3.1) | 4 (3.1) | 0.799 | 0.371 | 0.067 | 0.796 | |||
| PL-12 | 7 (7.9) | 1 (1.1) | 1 (1.1) | 5 (5.6) | 7 (5.4) | 3 (2.3) | 0 | 4 (3.1) | 0.543 | 0.461 | 1.034 | 0.309 | |||
| EJ | 0 (0.0) | 0 | 0 | 0 | 10 (7.7) | 1 (0.8) | 1 (0.8) | 8 (6.2) | - | 0.006 | 6.744 | 0.009 | |||
| OJ | 2 (2.2) | 2 (2.25) | 0 | 0 | 4 (3.1) | 3 (2.3) | 1 (0.8) | 0 | - | 1 | 0.336 | 0.562 | |||
| Myositis associated autoantibodies (MAAs) | |||||||||||||||
| PM-Scl100 | 6 (6.7) | 5 (5.6) | 1 (1.12) | 0 | 5 (3.8) | 1 (0.8) | 1 (0.8) | 3 (2.3) | 0.928 | 0.335 | 0.055 | 0.815 | |||
| PM-Scl75 | 6 (6.7) | 3 (3.4) | 1 (1.12) | 2 (2.2) | 9 (6.9) | 2 (1.5) | 4 (3.1) | 3 (2.3) | 0.003 | 0.958 | 0.089 | 0.766 | |||
| Ku | 9 (10.1) | 4 (4.5) | 2 (2.2) | 3 (3.4) | 4 (3.1) | 2 (1.5) | 1 (0.8) | 1 (0.8) | - | 0.041 | 4.218 | 0.040 | |||
| Ro-52 | 44 (49.4) | 8 (9.0) | 5 (5.6) | 31 (34.8) | 70 (53.8) | 4 (3.1) | 4 (3.1) | 62 (47.7) | 0 | 1 | 1.952 | 0.162 | |||
| Both MSAs and MAAs positive | 79 (88.8) | - | - | - | 112 (86.1) | - | - | - | 1.143 | 0.285 | - | - | |||
| Only MSAs positive | 62 (69.7) | - | - | - | 99 (76.1) | - | - | - | 0 | 0.989 | - | - | |||
| Only MAAs positive | 54 (60.1) | - | - | - | 79 (60.8) | - | - | - | 0.323 | 0.570 | - | - | |||