表 1.

抗tubulin-α-1C抗体阳性组与阴性组间实验室指标的比较

Clinical and laboratory characteristics of SSc patients with the elevated and normal levels of serum anti-tubulin-α-1C

Items	Anti-tubulin-α-1C(+)(n=29)	Anti-tubulin-α-1C(-)(n=33)	P
ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; RF, rheumatoid factor; ANA, antinuclear antibody; ACA, anti-centromere anti-bodies; CENP, centromere protein; aCL, anticardiolipin. * P＜0.05, statistically significant result.
Female，n(%)	26 (89.7)	31 (93.9)	0.537
Age/years, x±s	59.07±20.42	51.88±10.45	0.081
ESR /(mm/h), M(Min, Max)	21 (7-110)	12 (2-55)	0.033*
CRP/(mg/L)，M(Min, Max)	2.49 (0.54-73.90)	2.95 (0.38-44.21)	0.431
C3/(g/L)，x±s	0.87±0.23	0.87±0.26	0.966
C4/(g/L)，x±s	0.22±0.09	0.24±0.26	0.667
RF/(IU/mL)，M(Min, Max)	20 (20-123)	20 (18-3 710)	0.781
Anti-Ro52 positive，n(%)	8 (27.6)	16 (48.5)	0.090
Anti-RNP positive，n(%)	7 (24.1)	9 (27.3)	0.780
Anti-Scl-70 positive，n(%)	11 (37.9)	5 (15.2)	0.041*
ANA positive，n(%)	23 (79.3)	20 (60.6)	0.110
ACA positive，n(%)	10 (34.5)	4 (12.1)	0.035*
CENP A or B positive，n(%)	6 (20.7)	6 (18.2)	0.803
aCL positive，n(%)	4 (13.8)	0	0.043*
Anti-dsDNA positive，n(%)	4 (13.79)	1 (3.03)	0.120
IgA/(g/L), x±s	3.37±2.89	2.52±1.80	0.164
IgG/(g/L), x±s	15.30±6.61	14.60±6.82	0.681
IgM/(g/L), x±s	1.17±0.81	0.99±0.70	0.350
Raynaud's phenomenon，n(%)	15 (71.4)	6 (37.5)	0.039*