Scheme 1. Synthetic Route of FQ393: (i) (Boc)2O, 1,4-Dioxane, and NaOH (2 M); (ii) MeCN at RT; (iii) Cs2CO3, Pd2(dba)3, X-Phos, and MeCN at 100 °C; (iv) Hydrogen Chloride in Ethyl Acetate (4 M).
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