Effects on
cell viability of hot water extracts of herbs on CRC
cell lines. HCT116, HT-29, SW620, or DLD-1 cells were seeded in 96-well
plates at a density of 2000 cells/well and incubated overnight. Cells
were then treated with hot water extracts of herbal tea with a concentration
of 100, 500, and 1000 μg/mL for 48 h. After 48 h treatment,
cell viability was measured by the MTS assay at 490 nm. The results
were normalized to water control and shown in mean (% of control)
± SD of three sampled replicates. Dash lines indicate 100% viability.
*, p < 0.01; **, p < 0.001;
***, and p < 0.0001 compares the 100 μg/mL
of extracts to the swater control. #, p < 0.01;
##, p < 0.001; and ###, p <
0.0001 compares the 500 μg/mL of extracts to the water control.
+, p < 0.01; ++, p < 0.001;
and +++, p < 0.0001 compares the 1000 μg/mL
of extracts to water control.