Table 1.
Demographics and patient characteristics.
| Characteristics | Methylprednisolone | P | |
|---|---|---|---|
| No (N = 38) | Yes (N = 37) | ||
| Age | 72.5 [34-92] | 73 [48-93] | .78 |
| Male | 21 (55%) | 23 (62%) | .54 |
| BMI | 28 [14.7-50.1] | 26.6 [20.1-50.2] | .42 |
| Diabetes | 20 (53%) | 23 (62%) | .40 |
| Hypertension | 26 (68%) | 33 (89%) | .03 |
| CAD | 6 (16%) | 4 (11%) | .52 |
| Previous stroke | 4 (11%) | 3 (8%) | .72 |
| MAP < 70 at admission | 17 (45%) | 12 (32%) | .27 |
| GCS | 14 [3-15] | 15 [5-15] | .05 |
| SCR at admission | 1.7 [0.6-15.7] | 1.5 [0.9-10.0] | .19 |
| PaO2 at admission | 67.6 [30.9-227.0] | 72.0 [23.0-275.0] | .37 |
| PaO2/FiO2 ratio | 97.5 [41.0-568.0] | 95.9 [41.6-575.0] | .81 |
| Admission month | |||
| March | 19 (79%) | 5 (21 %) | .0007 |
| April | 19 (37%) | 32 (63%) | |
| Treatment | |||
| HCQ & AZI | 25 (65%) | 27 (73%) | .21 |
| HCQ&AZI&TOC | 3 (8%) | 6 (16%) | |
| Other | 10 (17%) | 4 (11%) | |
| Anticoagulation | 6 (16%) | 19 (51%) | .001 |
| Vassopressors | 10 (26%) | 8 (22%) | .63 |
| Mechanical ventilated | 16 (42%) | 15 (41%) | .89 |
| Hemodialysis | 7 (18%) | 6 (16%) | .80 |
| AKI during hospitalization | 14 (37%) | 14 (38%) | .92 |
Source: Results are reported as number (percentage or range).
Abbreviations: AKI, acute kidney injury; AZI, azithromycin; BMI, body mass index; CAD, coronary artery disease; FiO2, fraction of inspired oxygen; HCQ, hydroxychloroquine; GCS, glasgow coma scale; MAP, mean arterial pressure; PaO2, partial pressure of oxygen in arterial blood; SCR, serum creatinine; TOC, tocilizumab.